Biography
I’m a postdoc at Columbia University, I work with Dr. Yufeng Shen and study computational biology and human genetics. Before that, I got my PhD degree of Bioinformatics from Peking Univeristy. During that time, I developped computational tools to investigate phase separation and protein degradation with Dr. Tingting Li, including PhaSepDB and PhaSepPred. I was born in Zhucheng, Shandong, China. I like basketball, photography and skiing. (update: Sep 2023)
Interests
- Protein language model
- Functional Analysis of Genetic Mutations
- Precision medicine based on multi-omics data
- Drug designation and effect prediction via deep learning
- Studying cell differentiation and drug response using single-cell data
Education
Postdoc, 2023-
Columbia University
PhD of Bioinformatics, 2020-2023
Peking University
Bachelor of Medicine and Economics, 2015-2020
Peking University
Projects
Bioinformatics tools for phase seperation
PhaSepDB, PhaSePred and MloDisDB
Bioinformatics tools for protein degradation
Degpred-predict degron via deep learning
Main Publications
Quickly discover relevant content by filtering publications.
(2023).
Investigating phase separation properties of chromatin-associated proteins using gradient elution of 1,6-hexanediol.
BMC Genomics.
(2023).
PhaSepDB in 2022: annotating phase separation-related proteins with droplet states, co-phase separation partners and other experimental information.
Nucleic Acids Research.
(2022).
Systematic prediction of degrons and E3 ubiquitin ligase binding via deep learning.
BMC Biology.
(2022).
Screening membraneless organelle participants with machine-learning models that integrate multimodal features.
Proc Natl Acad Sci U S A.
(2022).
Serum Antigenome Profiling Reveals Diagnostic Models for Rheumatoid Arthritis.
Frontiers in Immunology.
Gallery
Contact
- ch3849@cumc.columbia.edu
- +1 201 927 3548
- 1130 St Nicholas Ave, New York, NY 10032