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SeqDance: A Protein Language Model for Representing Protein Dynamic Properties
Proteins perform their functions by folding amino acid sequences into dynamic structural ensembles. Despite the important role of …
Chao Hou 侯超, Yufeng Shen
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SeqDance: A Protein Language Model for Representing Protein Dynamic Properties
Investigating phase separation properties of chromatin-associated proteins using gradient elution of 1,6-hexanediol
Chromatin-associated phase separation proteins establish various biomolecular condensates via liquid-liquid phase separation (LLPS), …
Peiyu Zhu, Chao Hou 侯超, Manlin Liu, Taoyu Chen, Tingting Li, Likun Wang
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Investigating phase separation properties of chromatin-associated proteins using gradient elution of 1,6-hexanediol
PhaSepDB in 2022: annotating phase separation-related proteins with droplet states, co-phase separation partners and other experimental information
Phase separation (PS) proteins form droplets to regulate myriad membraneless organelles (MLOs) and cellular pathways such as …
Chao Hou 侯超, Xinxin Wang, Haotai Xie, Taoyu Chen, Peiyu Zhu, Xiaofeng Xu, Kaiqiang You, Tingting Li
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PhaSepDB in 2022: annotating phase separation-related proteins with droplet states, co-phase separation partners and other experimental information
Systematic prediction of degrons and E3 ubiquitin ligase binding via deep learning
Degrons are short linear motifs, bound by E3 ubiquitin ligase to target protein substrates to be degraded by the ubiquitin-proteasome …
Chao Hou 侯超, Yuxuan Li, Mengyao Wang, Hong Wu, Tingting Li
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Systematic prediction of degrons and E3 ubiquitin ligase binding via deep learning
Screening membraneless organelle participants with machine-learning models that integrate multimodal features
Protein self-assembly is one of the formation mechanisms of biomolecular condensates. However, most phase-separating systems (PS) …
Zhaoming Chen, Chao Hou 侯超, Liang Wang, Chunyu Yu, Taoyu Chen, Boyan Shen, Yaoyao Hou, Pilong Li, Tingting Li
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Screening membraneless organelle participants with machine-learning models that integrate multimodal features
Serum Antigenome Profiling Reveals Diagnostic Models for Rheumatoid Arthritis
Serum antigens were captured from a cohort consisting of 60 RA patients (45 ACPA-positive RA patients and 15 ACPA-negative RA …
Peng Han, Chao Hou 侯超, Xi Zheng, Lulu Cao, Xiaomeng Shi, Xiaohui Zhang, Hua Ye, Hudan Pan, Liang Liu, Tingting Li, Fanlei Hu, Zhanguo Li
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Serum Antigenome Profiling Reveals Diagnostic Models for Rheumatoid Arthritis
MloDisDB: a manually curated database of the relations between membraneless organelles and diseases
Cells are compartmentalized by numerous membrane-bounded organelles and membraneless organelles (MLOs) to ensure temporal and spatial …
Chao Hou 侯超, Haotai Xie, Yang Fu, Yao Ma, Tingting Li
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MloDisDB: a manually curated database of the relations between membraneless organelles and diseases